UNIVERSIDAD PERUANA
CAYETANO  HEREDIA

Facultad de Ciencias y Filosofía
Departamento de Bioquímica,
Biología Molecular y Farmacología

     A la vanguardia de la Ciencia

Publicaciones

Decuypere S., Vandesompele J., Yardley V., De Doncker S., Laurent T., Rijal S., Llanos-Cuentas A., Chappuis F., Arévalo J., Dujardin J-C. Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology, 2005.

Garcia, A.L., Kindt, A., Llanos, A., Bermudez, H., Arevalo, J., Bañuls, A.L., Tibayrenc, M., De Doncker, S., Le Ray, D. & Dujardin, J.C. (2004) American tegumentary leishmaniasis: antigen-gene polymorphism, taxonomy and clinical pleomorphism. Infection, Genetics and Evolution, Infect Genet Evol. 2005 Mar;5(2):109-116.

Caceres, A., Villaseca, P., Dujardin, J.C., Bañuls, A.L., Inga, R., Lopez, M, . Arana, M. and J. Arevalo. (2004). Lutzomyia ayacuchensis, (Dipter: Psychodidae) vector of Andean cutaneous Lesihamaniasis (Uta) in Parinacochas,Ayacucho, South Peru. Amer. J. Trop. Med. Hyg. 70(6): 607-12.

Garcia, L., Kindt, A., Bermudez, H., Llanos Cuentas, A., De Doncker, S., Arevalo, J., Quispe, KW. and Dujardin, JC. (2004). Culture-independent species typing of Neotropical Leishmania: clinical validation of a PCR-based assay targeting heat shock protein 70 genes. J. Clin. Microbiol. 42: 2294-7.

Victoir, K., De Doncker, S. Cabrera, L., Alvarez, E., Arevalo, J., Llanos Cuentas, A., Le Ray, D. and Dujardin, J.C. (2003). Direct identification of Leishmania specie in biopsies from patients with American Tegumentary Leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 97: 80-87.

St Hilaire PM, Alves LC, Herrera F, Renil M, Sanderson SJ, Mottram JC, Coombs GH, Juliano MA, Juliano L, Arevalo J, Meldal M. (2002). Solid-phase library synthesis, screening, and selection of tight-binding reduced peptide bond inhibitors of a recombinant Leishmania mexicana Cysteine protease B. J Med Chem. 2002 May 9;45(10):1971-82.

Dujardin JC, Victoir K, De Doncker S, Guerbouj S, Arévalo J, Le Ray D. (2002). Molecular epidemiology and diagnosis of Leishmania: what have we learnt from genome structure, dynamics and function? Trans R Soc Trop Med Hyg. (Apr) 96 Suppl 1: 81-86.

Zimic, M. , Guerra D. & Arévalo J. (2002).
DNA Thermodynamics pressure: a potential contributor to genome evolution. Trans Roy Soc Trop Med Hyg. 96 Suppl 1: 15-20

DNA thermodynamic pressure: a potential contributor to genome evolution. 2002. Zimic MJ, Guerra D, Arevalo J. Trans R Soc Trop Med Hyg. 96 Suppl 1:S15-20.

Oberhelman RA, Gilman RH, Sheen P, Cordova J, Taylor DN, Zimic M, Meza R, Perez J, LeBron C, Cabrera L, Rodgers FG, Woodward DL, Price LJ. 2003. Campylobacter transmission in a Peruvian shantytown: a longitudinal study using strain typing of campylobacter isolates from chickens and humans in household clusters. J Infect Dis. 15;187(2):260-9.

Patricia Sheen, Cesar Lopez, Melissa Mendez, Jaeson Calla , Lizeth Peña y Mirko Zimic
Aspectos moleculares de la resistencia a pirazinamida en M.tuberculosis: Implicancias para el desarrollo de nuevos métodos de diagnóstico y terapéutica. Revista Peruana de Neumología - Nov. 2005

Tom F Pelly, Carlos Santillan, Robert H Gilman, Lillia Cabrera, Edwin Garcia, Carlos Vidal, Mirko Zimic, David A Moore,Carlton A Evans.Tuberculosis Skin Testing, Anergy and Protein Malnutrition in Peru.
International Journal of TB and lung disease - In press.

Oberhelman RA, Gilman RH, Sheen P, Cordova J, Zimic M, Cabrera L, Meza R, Perez J. Related Articles, Links  An intervention-control study of corralling of free-ranging chickens to control Campylobacter infections among children in a Peruvian periurban shantytown.
Am J Trop Med Hyg. 2006 Jun;74(6):1054-9.

Chinga-Alayo E, Villena J, Evans AT, Zimic M. Related Articles, Links  Thyroid hormone levels improve the prediction of mortality among patients admitted to the intensive care unit.
Intensive Care Med. 2005 Oct;31(10):1356-61. Epub 2005 Jul 13.

Caceres AG, Villaseca P, Dujardin JC, Banuls AL, Inga R, Lopez M, Arana M, Le Ray D, Arevalo J.  Epidemiology of Andean cutaneous leishmaniasis: incrimination of Lutzomyia ayacuchensis (Diptera: psychodidae) as a vector of Leishmania in geographically isolated, upland valleys of Peru. Am J Trop Med Hyg. 2004 Jun;70(6):607-12.

Inga R, De Doncker S, Gomez J, Lopez M, Garcia R, Le Ray D, Arevalo J, Dujardin JC. Relation between variation in copy number of ribosomal RNA encoding genes and size of harbouring chromosomes in Leishmania of subgenus Viannia. Mol Biochem Parasitol. 1998 May 1;92(2):219-28.

Perez JE, Ogusuku E, Inga R, Lopez M, Monje J, Paz L, Nieto E, Arevalo J, Guerra H. Natural Leishmania infection of Lutzomyia spp. in Peru.Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):161-4.

Lopez M, Inga R, Cangalaya M, Echevarria J, Llanos-Cuentas A, Orrego C, Arevalo J. Diagnosis of Leishmania using the polymerase chain reaction: a simplified procedure for field work.Am J Trop Med Hyg. 1993 Sep;49(3):348-56.

Lopez M, Inga R, Cueva N, Alvarez E, Arevalo J. No abstract PCR: a tool for diagnosis of American tegumentary leishmaniasis in a health post of rural endemic areas. Arch Inst Pasteur Tunis. 1993 Jul-Oct;70(3-4):499-504.

Taype, C.A., Castro, J.C., Accinelli, R.A., Herrera-Velit, P., Shaw, M.A., Espinoza, J.R.  2006.  Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian population.  Infection, Genetics and Evolution.

Marcos, L., Maco, V., Samalvides, F. Terashima, A., Espinoza, J.R., Gotuzzo, E.  2006.  Risk factors for Fasciola hepatica infection in children: a case-control study. 
Trans R Soc Trop Med Hyg. 100(2):158-66

Marcos, L., Maco, V., Terashima, A., Samalvides, F. Espinoza, J.R., Gotuzzo, E. 
2005.  Fascioliasis in relatives of patients with Fasciola hepatica infection in Peru.  Rev Inst Med Trop Sao Paulo. 47(4):219-22.

Timoteo, O., Maco, V. Jr., Maco, V., Neyra, V., Yi, P.J., Leguía, G., Espinoza, J.R.  2005.  Characterization of the humoral immune response in alpacas (Lama pacos) experimentally infected with Fasciola hepatica against cysteine proteinases Fas1 and Fas2 and histopathological findings.  Vet Immunol Immunopathol. 106(1-2):77-86.

Espinoza, J.R., Timoteo, O., Herrera-Velit, P2005.  Fas2-ELISA in the detection of human infection by Fasciola hepatica.  Journal of Helminthology 79(3):235-40.

Raymundo, L.A., Flores, V.M., Terashima, A., Samalvides, F., Miranda, E., Tantalean, M., Espinoza, J.R., Gotuzzo, E.  2004.  Hyperendemicity of human fasciolosis in the Mantaro Valley, Peru: factors for infection with Fasciola hepatica.  Rev Gastroenterol Peru. 24(2):158-64. Spanish.

Neyra, V., Chavarry, E., Espinoza, J.R2002.  Cysteine proteinases Fas1 and Fas2 are diagnostic markers for Fasciola hepatica infection in alpacas (Lama pacos).  Vet Parasitol. 105(1):21-32.

Cordova, M., Reategui, L., Espinoza, J.R1999.  Immunodiagnosis of human fascioliasis with Fasciola hepatica cysteine proteinases.  Trans R Soc Trop Med Hyg.  93(1):54-7

Hmama, Z., Knutson, K.L., Herrera-Velit, P., Nandan, D., and Reiner, N.E.  1999.  Monocyte adherence induced by lipopolysaccharide involves CD14, .LFA-1, and cytohesin-1.  Regulation by Rho and phosphatidylinositol 3-kinase.  Journal of Biological Chemistry 274(2): 1050-1057.

Hmama, Z., Nandan, D., Sly, L. Knutson, K.L., Herrera-Velit, P., and Reiner, N.E.  1999.  1a,25-dihydroxyvitamin D3-induced myeloid cell differentiation is regulated by a Vitamin D signaling complex.  Journal of Experimental Medicine 190 (11): 1583-1594.

Knutson, K. L., Hmama, Z., Herrera-Velit, P., Rochford, R., and Reiner, N. E.  1998.  Lipoarabinomannan of Mycobacterium tuberculosis promotes protein tyrosine dephosphorylation and inhibition of MAP kinases in human mononuclear phagocytes:  Role of the Src homology 2-containing tyrosine phosphatase, SHP-1.  Journal of Biological Chemistry 273(1): 645-652.

Martens, J.S., Reiner, N.E., Herrera-Velit, P. and Steinbrecher, U.P.  1998.  Phosphatidylinositol 3-kinase is involved in the induction of macrophage growth by oxidized low density lipoprotein.  Journal of Biological Chemistry 273(9): 4915-4920

Cordova, M., Herrera, P., Nopo, L., Bellatin, J., Naquira, C., Guerra, H., Espinoza, J.R.  1997.  Fasciola hepatica cysteine proteinases: immunodominant antigens in human fascioliasis.  Am J Trop Med Hyg.  57(6):660-6.

Herrera-Velit, P., Knutson, K. L., and Reiner, N. E.  1997.  Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-z in bacterial lipopolysaccharide-treated human monocytes.  Journal of Biological Chemistry 272(26): 16445-16452. 

Cordova, M., Herrera, P., Ñopo, L., Bellatin, J., Naquira, C., Guerra, H., and Espinoza, J. R. 1997.  Cysteine proteinases: Immunodominant antigens in human fascioliasis.  American Journal of Tropical Medicine and Hygiene. 5: 660-666. 

Herrera-Velit, P. and Reiner, N. E.  1996.  Bacterial lipopolysaccharide induces the association and coordinate activation of p53/56lyn and phosphatidylinositol 3-kinase in human monocytes.  Journal of Immunology 156: 1157-1165. 

Espinoza, J.R., Skineer, A.C., Davis, C.R., Llanos-Cuentas, A., Arevalo, J., Dye, C., McMaster, W.R., Ajioka, J.W., Blackwell, J.M.  1995.  Extensive polymorphism at the Gp63 locus in field isolates of Leishmania peruviana.  Mol Biochem Parasitol. 72(1-2):203-13

Liu, M. K., Herrera-Velit, P., Brownsey, R. W., and Reiner, N. E.  1994.  CD14-dependent activation of protein kinase C and mitogen activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide.  Journal of Immunology 153: 2642-2652.

Rege, A. A., Herrera, P., Lopez, M., and Dresden, M. H.  1989.  Isolation and characterization of a cysteine proteinase from Fasciola hepatica adult worms.  Molecular and Biochemical Parasitology 35: 89-96.
 

 

 

 

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